Done at diagnosis, it is the most precise way to diagnose CML as well as provide helpful information about your specific case of CML. An analysis of bone marrow samples confirms the presence of the Philadelphia chromosome and if other abnormalities are present.
The bone marrow biopsy may be referred ot as a BMA/BMB. It may be performed in a hospital or in the specialist’s office. A local anesthetic will be administered, usually in the hip bone area, and you will likely feel a stinging sensation for a few seconds. Once the area is numbed, a needle is inserted to draw out the liquid marrow (aspirate). Another needle may be used to take a sample of the solid bone marrow (biopsy). In most cases this procedure does not take very long and is relatively painless. But if you are the sort of person who feels anxious about these types of tests, speak to your doctor. He or she may prescribe a medication to help you relax.