CML Glossary ‘N’
*NCCN = National Comprehensive Cancer Network; this American group has prepared guidelines in CML management to direct physician care with respect to CML; along with ELN guidelines, NCCN guidelines are considered to be the minimum standard of care for CML patients.
Neutrophils = the type of myeloid white blood cell which is most increased in CML. Also referred to as polys (polymorphonuclear leukocytes); granulocytes (though this term also includes other types of white cells, such as basophils and eosinophils); and neutrophils.
Nilotinib = generic name for the oral tyrosine kinase cancer inhibitor that targets bcr-abl, KIT, and platelet derived growth factor receptor (PDGFR). It is 80 times more potent than Gleevec.
NMDP = National Marrow Donor Program
*NMSCT = non-myeloablative stem cell transplant (“mini-transplant”).
Also called NST
*Non-myeloablative (as in non-myeloablative stem cell transplant):
myelo = marrow; ablative = destructive. So non-myeloablative stem cell transplant is one in which the patient’s marrow is not totally destroyed prior to receiving the donors stem cells.
NSAID = nonsteroidal anti inflammatory drugs – such as ibuprofen, naproxen, etc.
Neutropenia = an unusually low number of neutrophils
*NST = another acronym for non-myeloablative stem cell transplant.